The i-STAT is a reliable POC device and can be used in field condition to assess electrolyte status in cattle. The i-STAT had 76–100% Se and 87.7–100% Sp for assessing electrolyte statuses.Ĭonclusions and Clinical Importance: The i-STAT yielded results that were in agreement with the auto-analyzer, with negligible biases in measurement of plasma K+, Na+, and CI concentrations. The mean bias (blood concentration - plasma concentration) was 0.20 for K+ (P =. Regression equations fitting blood (Y) and plasma (X) concentration did not deviate from the identity line for K+ (Y = 0.10 + 0.98 9 X), Na+ (Y = X), and CI (Y = 3.04 + 0.96 9 X). The i-STAT results were highly correlated with the Cobas C501 results (r = 0.970, 0.922, and 0.866 for K+, Na+, and CI, respectively). Plasma and blood Na+ concentrations were similar (136.95 versus 136.8 mmol/L). 04) were greater than their concentrations in blood. Results: Plasma concentrations of K+ (4.39 versus 4.2 mmol/L P <. Blood and plasma electrolyte data were subjected to student t-test for comparison, the concordance analysis for agreement, accuracy, and precision, the Passing-Bablok regression and the Bland-Altman plot for reliability, and receiver operating characteristics curves for sensitivity (Se) and specificity (Sp). Methods: In this prospective study, blood samples collected from the jugular vein were processed for determination of K+, Na+, and CI concentrations in blood and plasma using the i-STAT and auto-analyzer (Cobas C501), respectively. Objective: To evaluate reliability of the i-STAT, a point-of-care (POC) device, in measuring blood K+, Na+, and CI concentrations in cattle.Īnimals: Ninety-eight cattle with various diseases. Background: Rapid determination of blood electrolyte concentrations can help determine electrolyte status and delivery of effective volume of electrolyte solutions in field conditions.
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